Abstract
We present the case of a 61-year-old woman with anaphylaxis after ingesting ice creams containing erythritol as a sweetener. After a detailed study of the ingredients of the ice cream after each episode, the only component in common was erythritol. This sweetener has recently been used in Europe as an artificial additive in many types of food and drink, mainly because it does not contain calories. Therefore, food and drink additives should be included in the differential diagnosis of food allergic reactions. This is the first record of an allergic reaction caused by erythritol in Europe.
References
Hino H, Kasai S, Hattori N, Kenjo K. A case of allergic urticaria caused by erythritol. J Dermatol. 2000;27:163-5.
Venkatesh YP, Hedge VL. A hypothesis for the mechanism of immediate hypersensitivity to mannitol. Allergol Int 2003;52:165-70.
Yunginger JW, Jones RT, Kita H, Saito K, Hefle SL, Taylor SL. Allergic reactions after ingestion of erythytol-containing foods and beverages. J Allergy Clin Immunol. 2001;108:650.
Kurihara K, Suzuki T, Unno A, Hatano M. A case of 5 year-old boy of anaphylaxis due to erythritol with negative prick test and positive intradermal test. J Jpn Soc Allergol 2013;62(11):1534-40. Japanese.
Sugiura S, Kondo Y, Ito K, Hashiguchi A, Takeuchi M, Koyama N. A case of anaphylaxis to erythritol diagnosed by CD203c expression-based basophil activation test. Ann Allergy Asthma Immunol 2013; 111: 222-3.
Shirao K, Inoue M, Tokuda R, Nagao M, Yamaguchi M, Okahata H, et al. “Bitter Sweetâ€: a child case of erythritol induced anaphylaxis. Allergol Int 2013;62:269-71.
Shimizu Y, Kijima A, Matsui S, Maeda N, Nishino H, Kataoka,Y. A case of urticaria caused by erythritol. J Environ Dermatol Cutan Allergol, 2012:6: 90-4.
Sugiura S, Kondo Y, Tsuge I, Nakagawa T, Kando N, Ito K, et al. IgE-dependent mechanism and successful desensitization of erythritol allergy. Ann Allergy Asthma Immunol 2016;2016:320-21.
Sreenath K, Prabhasankar P, Venkatesh YP. Generation of an antibody specific to erythritol, a non-immunogenic food additive. Food Addit Contam 2006:23(9):861
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